Rh proteins mediated ammonia excretion in the skin of zebrafish larvae: evidence of active ammonia transport by ionocytes

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Rhcg1 and Rhbg mediate ammonia excretion by ionocytes and keratinocytes in the skin of zebrafish larvae: H+-ATPase-linked active ammonia excretion by ionocytes.

In zebrafish, Rhcg1 was found in apical membranes of skin ionocytes [H⁺-ATPase-rich (HR) cells], which are similar to α-type intercalated cells in mammalian collecting ducts. However, the cellular distribution and role of Rhbg in zebrafish larvae have not been well investigated. In addition, HR cells were hypothesized to excrete ammonia against concentration gradients. In this study, we attempt...

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Ammonia excretion by the skin of zebrafish (Danio rerio) larvae.

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2013

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fasebj.27.1_supplement.1115.25